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Á¦¸ñ | Validation of SwimCount¢â, a Novel Home-Based Device That Detects Progressively Motile Spermatozoa: Correlation with World Health Organization 5th Semen Analysis | µî·ÏÀÏ | 20201007 | ´Ù¿î·Îµå | |
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Purpose: We evaluated the usefulness of a home-based device (SwimCount¢â) compared with World Health Organization (WHO) 5th semen analysis in screening for male fertility in Asian men.
Materials and methods: One hundred Asian men who visited CHA Seoul Station Fertility Center for evaluation of fertility were included. Semen samples were analyzed and compared with the SwimCount¢â results. An aliquot of 0.5 mL of the semen sample was added to the SwimCount¢â and a WHO 5th semen analysis was performed. Results were categorized as low (<5¡¿10⁶/mL), and normal to high (¡Ã5¡¿10⁶/mL) total progressively motile sperm concentration. Receiver operating characteristic curve analysis was performed to evaluate the accuracy of the SwimCount¢â. Results: The mean total progressively motile sperm concentration was 26.7¡¿10⁶/mL. Semen analysis revealed that 28% of the samples were below the threshold count of 5 million/mL total progressively motile sperm concentration. The mean total progressively motile sperm concentration of the light color SwimCount¢â result group determined by semen analysis was 7.5¡¿10⁶/mL, and the mean total progressively motile sperm concentration of the moderate to dark color SwimCount¢â result group was 34.2¡¿10⁶/mL. An area under the receiver operating characteristic curve of 0.85 (95% confidence interval, 0.77-0.94; p<0.001) was obtained when the SwimCount¢â was compared with semen analysis. The sensitivity and specificity were obtained at a cut off value of 5.0¡¿10⁶/mL total progressively motile sperm concentration, giving a sensitivity and specificity of 87.5% and 73.4%. |
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